Instance ID10585
Regular Expressionxx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x
Motif InstanceSNLNPNAKEFVPG
Bait Uniprot AccessionQ9BPZ3
Bait Uniprot IdentifierPAIP2_HUMAN
Bait Gene NamePAIP2
Bait OrganismHomo sapiens (Human)
Sequence Position109-121
Critical ResiduesP3; P10
Motif PTM(s)Unknown
Secondary StructureBeta turn
Experimental Method(s)Co-IP; SPR; ITC; NMR; Mutation analysis; Pull down; X-ray crystallography
Interaction ID20585
Interacting DomainMLLE domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16601676, 14685257, 20096703
CommentsThe PABP-interacting motif 2 (PAM2) in human PABP-interacting protein 2 (PAIP2) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)