Instance ID10587
Regular Expressionxx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x
Motif InstanceSKLSVNAPEFYPS
Bait Uniprot AccessionQ9H074
Bait Uniprot IdentifierPAIP1_HUMAN
Bait Gene NamePAIP1
Bait OrganismHomo sapiens (Human)
Sequence Position126-138
Critical ResiduesP3; P10
Motif PTM(s)Unknown
Secondary StructureBeta turn
Experimental Method(s)ITC; NMR; SPR; Pull down; Mutation analysis; Far Western blotting; Co-IP
Interaction ID20587
Interacting DomainMLLE domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16554297, 14685257, 11997512
CommentsThe PABP-interacting motif 2 (PAM2) in human PABP-interacting protein 1 (PAIP1) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)