Instance ID10589
Regular Expressionxx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x
Motif InstanceSTLNPNAKEFNPR
Bait Uniprot AccessionQ99700
Bait Uniprot IdentifierATX2_HUMAN
Bait Gene NameATXN2
Bait OrganismHomo sapiens (Human)
Sequence Position912-924
Critical ResiduesP3; P5; P7; P10
Motif PTM(s)Unknown
Secondary StructureBeta turn
Experimental Method(s)ITC; NMR; SPR; X-ray crystallography
Interaction ID20589
Interacting DomainMLLE domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16554297, 20181956
CommentsThe PABP-interacting motif 2 (PAM2) in human Ataxin-2 (ATXN2) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)