Instance ID10591
Regular Expressionxx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x
Motif InstanceTGLNPNAKVWQEI
Bait Uniprot AccessionQ71RC2
Bait Uniprot IdentifierLARP4_HUMAN
Bait Gene NameLARP4
Bait OrganismHomo sapiens (Human)
Sequence Position13-25
Critical ResiduesP3; P10
Motif PTM(s)Unknown
Secondary StructureBeta turn
Experimental Method(s)Mutation analysis; ITC; X-ray crystallography
Interaction ID20591
Interacting DomainMLLE domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)21098120
CommentsThe PABP-interacting motif 2 (PAM2) in human La-related protein 4 (LARP4) that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)