Instance ID10606
Regular Expressionxx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x
Motif InstanceSQLSPNAKEFVYN
Bait Uniprot AccessionQ14106
Bait Uniprot IdentifierTOB2_HUMAN
Bait Gene NameTOB2
Bait OrganismHomo sapiens (Human)
Sequence Position251-263
Critical ResiduesP10
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Pull down; Mutation analysis; SPR; ITC
Interaction ID20606
Interacting DomainMLLE domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17785442, 16554297
CommentsThe PAM2 motif (251-263) in human TOB2 that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)