Instance ID10608
Regular Expressionxx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x
Motif InstanceQTPNPTASEFIPK
Bait Uniprot AccessionQ58A45
Bait Uniprot IdentifierPAN3_HUMAN
Bait Gene NamePAN3
Bait OrganismHomo sapiens (Human)
Sequence Position284-296
Critical ResiduesP10
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Co-IP; Pull down; ITC; NMR
Interaction ID20608
Interacting DomainMLLE domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)18056425, 17595167
CommentsThe PAM2 motif in human PAB-dependent poly(A)-specific ribonuclease subunit PAN3 that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)