Instance ID10610
Regular Expressionxx[LFP][NS][PIVTAFL]xAxx(([FY]x[PYLF])|(Wxx))x
Motif InstanceNSFNPEAQVFMPI
Bait Uniprot AccessionP50616
Bait Uniprot IdentifierTOB1_HUMAN
Bait Gene NameTOB1
Bait OrganismHomo sapiens (Human)
Sequence Position130-142
Critical ResiduesP10
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Pull down; Mutation analysis; ITC; NMR
Interaction ID20610
Interacting DomainMLLE domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17785442, 20595394
CommentsThe PAM2 motif (130-142) in human TOB1, an antiproliferative transcription factor, that mediates binding to the MLLE domain of Polyadenylate-binding protein 1 (PABP1/PABPC1/PABPC2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)