Instance ID10615
Regular Expression((^x{0,3})|(Q))x[^FHWY][ILM][^P][^FHILVWYP][HFM][FMY]xx
Motif InstanceQGRLDGFFQV
Bait Uniprot AccessionP26793
Bait Uniprot IdentifierFEN1_YEAST
Bait Gene NameRAD27
Bait OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence Position340-349
Critical ResiduesP7; P8
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis
Interaction ID20615
Interacting DomainPCNA, C-terminal domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10409728
CommentsThe PCNA binding PIP box motif in Saccharomyces cerevisiae Flap endonuclease 1 (Fen1/Rad27) that mediates interactions with the yeast replication clamp proliferating cell nuclear antigen (PCNA/POL30)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)