Instance ID10620
Regular Expression((^x{0,3})|(Q))x[^FHWY][ILM][^P][^FHILVWYP][HFM][FMY]xx
Motif InstanceQTSMTDFYHS
Bait Uniprot AccessionP38936
Bait Uniprot IdentifierCDN1A_HUMAN
Bait Gene NameCDKN1A
Bait OrganismHomo sapiens (Human)
Sequence Position144-153
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)X-ray crystallography
Interaction ID20620
Interacting DomainPCNA, C-terminal domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)8861913
CommentsThe C-terminal PCNA binding PIP box motif of human Cyclin-dependent kinase inhibitor 1 (CDKN1A/p21/WAF1/CIP1) that mediates interaction with human Proliferating cell nuclear antigen (PCNA/Cyclin)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)