Instance ID10623
Regular Expression((^x{0,3})|(Q))x[^FHWY][ILM][^P][^FHILVWYP][HFM][FMY]xx
Motif InstanceQSSLLSFFSK
Bait Uniprot AccessionQ03834
Bait Uniprot IdentifierMSH6_YEAST
Bait Gene NameMSH6
Bait OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence Position27-36
Critical ResiduesP7; P8
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Mutation analysis
Interaction ID20623
Interacting DomainPCNA, C-terminal domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11062484
CommentsThe N-terminal PCNA binding PIP box motif of Saccharomyces cerevisiae DNA mismatch repair protein MSH6 that mediates interactions with the yeast replication clamp proliferating cell nuclear antigen (PCNA/POL30)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)