Instance ID10626
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceTNDSLL
Bait Uniprot AccessionP07550
Bait Uniprot IdentifierADRB2_HUMAN
Bait Gene NameADRB2
Bait OrganismHomo sapiens (Human)
Sequence Position408-413
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Far Western blotting; Mutation analysis; X-ray crystallography
Interaction ID20626
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11882663
CommentsThe amino-terminal PDZ domain of human Na(+)/H(+) exchange regulatory cofactor NHERF1 (SLC9A3R1), referred to as PDZ1, binds with high affinity to the C-terminal PDZ domain-binding motif of human Beta-2 adrenergic receptor

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)