Instance ID10627
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceAEDSFL
Bait Uniprot AccessionP09619
Bait Uniprot IdentifierPGFRB_HUMAN
Bait Gene NamePDGFRB
Bait OrganismHomo sapiens (Human)
Sequence Position1101-1106
Critical ResiduesP6
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Far Western blotting; Mutation analysis; X-ray crystallography
Interaction ID20627
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11882663
CommentsThe amino-terminal PDZ domain of human Na(+)/H(+) exchange regulatory cofactor NHERF1 (SLC9A3R1), referred to as PDZ1, binds with high affinity to the C-terminal PDZ domain-binding motif of human Platelet-derived growth factor receptor beta

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)