Instance ID10628
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceLFSTEV
Bait Uniprot AccessionP11274
Bait Uniprot IdentifierBCR_HUMAN
Bait Gene NameBCR
Bait OrganismHomo sapiens (Human)
Sequence Position1266-1271
Critical ResiduesP6
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)NMR
Interaction ID20628
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17473018
CommentsThe PDZ domain of human AF-6/MLLT4 binds to the C-terminal PDZ domain-binding motif of human Breakpoint cluster region protein (BCR) efficiently after phosphorylation of AF-6 by the BCR kinase

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)