Instance ID10629
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceLEITEL
Bait Uniprot AccessionQ9H251
Bait Uniprot IdentifierCAD23_HUMAN
Bait Gene NameCDH23
Bait OrganismHomo sapiens (Human)
Sequence Position3349-3354
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)NMR; Pull down(GST tag); Western blot
Interaction ID20629
Interacting DomainPDZ domain
Disease Association(s)Usher's Syndrome
Inhibitor(s)Unknown
Reference(s)19297620
CommentsThe second PDZ Domain of Harmonin (USH1C) specifically interacts with the C-terminal class 1 PDZ domain-binding motif of human Cadherin-23

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)