Instance ID10633
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceGYSTRL
Bait Uniprot AccessionQ13268
Bait Uniprot IdentifierDHRS2_HUMAN
Bait Gene NameDHRS2
Bait OrganismHomo sapiens (Human)
Sequence Position253-258
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)X-ray crystallography
Interaction ID20633
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17384233
CommentsC-terminal class 1 PDZ-binding motif in human Dicarbonyl reductase HEP27 or DHRS2 that binds to the PDZ domain of human Na(+)/H(+) exchange regulatory cofactor NHERF2 (SLC9A3R2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)