Instance ID10638
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceLEDSVF
Bait Uniprot AccessionQ01344
Bait Uniprot IdentifierIL5RA_HUMAN
Bait Gene NameIL5RA
Bait OrganismHomo sapiens (Human)
Sequence Position415-420
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)SPR; Co-IP; Y2H; Pull down; Mutation analysis; X-ray crystallography
Interaction ID20638
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11498591, 12842047
CommentsHuman Syntenin-1 (SDCBP), a protein containing PDZ domains, associates with the class 1 PDZ-binding motif in the cytoplasmic tail of human Interleukin-5 receptor subunit alpha (IL5RA)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)