Instance ID10641
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceEQVSAV
Bait Uniprot AccessionQ8TEU7
Bait Uniprot IdentifierRPGF6_HUMAN
Bait Gene NameRAPGEF6
Bait OrganismHomo sapiens (Human)
Sequence Position1596-1601
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)X-ray crystallography; Competition binding; NMR
Interaction ID20641
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20430886, 12095257
CommentsC-terminal class 1 PDZ-binding motif in human Rap guanine nucleotide exchange factor 6 (RAPGEF6) that binds to the PDZ domain of human Tyrosine-protein phosphatase non-receptor type 13 (PTPN13)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)