Instance ID10642
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceLEDTEL
Bait Uniprot AccessionQ495M9
Bait Uniprot IdentifierUSH1G_HUMAN
Bait Gene NameUSH1G
Bait OrganismHomo sapiens (Human)
Sequence Position456-461
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis; X-ray crystallography; ITC; Pull down(GST tag)
Interaction ID20642
Interacting DomainPDZ domain
Disease Association(s)Usher's Syndrome
Inhibitor(s)Unknown
Reference(s)20142502, 16283141, 12588794
CommentsC-terminal class 1 PDZ-binding motif in human Usher syndrome type-1G protein (USH1G/SANS) that binds to the first PDZ domain of Harmonin (USH1C)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)