Instance ID10652
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceQSSSSL
Bait Uniprot AccessionP31424
Bait Uniprot IdentifierGRM5_RAT
Bait Gene NameGrm5
Bait OrganismRattus norvegicus (Rat)
Sequence Position1198-1203
Critical ResiduesP2; P4; P5
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)X-ray crystallography; SPR; Mutation analysis
Interaction ID20652
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17396155
CommentsC-terminal class 1 PDZ-binding motif in rat Metabotropic glutamate receptor 5 (mGluR5/Grm5) that binds to the PDZ domain of rat Tamalin/Grasp

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)