Instance ID10655
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceSFLTWL
Bait Uniprot AccessionP46937
Bait Uniprot IdentifierYAP1_HUMAN
Bait Gene NameYAP1
Bait OrganismHomo sapiens (Human)
Sequence Position483-488
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)ITC; Pull down; Co-IP; Colocalization; Mutation analysis
Interaction ID20655
Interacting DomainPDZ domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)20868367
CommentsClass 1 PDZ-binding motif (483-488) in human YAP1 (Yes kinase-associated protein 1) that binds to the first PDZ domain of Tight junction protein ZO-2 (TJP2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)