Instance ID10665
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceLWETSI
Bait Uniprot AccessionQ9P0K1
Bait Uniprot IdentifierADA22_HUMAN
Bait Gene NameADAM22
Bait OrganismHomo sapiens (Human)
Sequence Position901-906
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Co-IP; Co-IP; Mutation analysis
Interaction ID20665
Interacting DomainPDZ domain
Disease Association(s)Epilepsy
Inhibitor(s)Unknown
Reference(s)16990550
CommentsC-terminal PDZ domain-binding motif in human Metalloproteinase-disintegrin ADAM22 that mediates binding to the PDZ domain of human Leucine-rich glioma-inactivated protein 1/ Epitempin-1 (LGI1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)