Instance ID10672
Regular Expressionxxx[ST]x[ACVILF]$
Motif InstanceLTASEV
Bait Uniprot AccessionQ66T02
Bait Uniprot IdentifierPKHG5_MOUSE
Bait Gene NamePlekhg5
Bait OrganismMus musculus (Mouse)
Sequence Position1068-1073
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP
Interaction ID20672
Interacting DomainPDZ domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)16467373
CommentsC-terminal class 1 PDZ-binding motif in mouse Synectin-binding RhoA exchange factor (Syx/Plekhg5) that binds to the PDZ domain of mouse PDZ adaptor protein synectin (Gipc1) leading to targeting of Syx to the plasma membrane

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)