Instance ID10674
Regular Expressionxxx[VLIFY]x[ACVILF]$
Motif InstanceEQPVYI
Bait Uniprot AccessionQ02410
Bait Uniprot IdentifierAPBA1_HUMAN
Bait Gene NameAPBA1
Bait OrganismHomo sapiens (Human)
Sequence Position832-837
Critical ResiduesP5
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Y2H; NMR; Mutation analysis
Interaction ID20674
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16007100
CommentsThe highly conserved C-terminal tail of human Adapter protein X11alpha folds back and inserts into the target-binding groove of its first PDZ domain forming an autoinhibited conformation

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)