Instance ID10681
Regular Expressionxxx[VLIFY]x[ACVILF]$
Motif InstanceGLDVPV
Bait Uniprot AccessionP04626
Bait Uniprot IdentifierERBB2_HUMAN
Bait Gene NameERBB2
Bait OrganismHomo sapiens (Human)
Sequence Position1250-1255
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)ITC; X-ray crystallography
Interaction ID20681
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12444095
CommentsThe C-terminal class 2 PDZ-binding motif of the human receptor tyrosine kinase ErbB2 (ERBB2) that binds to the PDZ domain of human ERBIN/LAP2 (ERBB2IP)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)