Instance ID10683
Regular Expressionxxx[VLIFY]x[ACVILF]$
Motif InstanceQEEFYA
Bait Uniprot AccessionP18827
Bait Uniprot IdentifierSDC1_HUMAN
Bait Gene NameSDC1
Bait OrganismHomo sapiens (Human)
Sequence Position305-310
Critical ResiduesP5
Motif PTM(s)Phosphorylation at Tyr-P5
Secondary StructureDisordered
Experimental Method(s)Pull down; Mutation analysis
Interaction ID20683
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19228696
CommentsThe C-terminal class 2 PDZ-binding motif of human Syndecan-1 (SDC1) that binds to the PDZ domain of human Syntenin-1 (SDCBP) on dephosphorylation of Tyr-309

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)