Instance ID10684
Regular Expressionxxx[VLIFY]x[ACVILF]$
Motif InstanceFHQFYI
Bait Uniprot AccessionP49768
Bait Uniprot IdentifierPSN1_HUMAN
Bait Gene NamePSEN1
Bait OrganismHomo sapiens (Human)
Sequence Position462-467
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Y2H; Colocalization; Co-IP; Pull down
Interaction ID20684
Interacting DomainPDZ domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10551805, 11083918
CommentsThe C-terminal class 2 PDZ-binding motif of human Presenilin-1 (PSEN1) that binds to the PDZ domain of human Adapter protein X11alpha (APBA1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)