Instance ID10693
Regular Expressionxx[RK]x{0,1}[VIL][^P][FW]x
Motif InstanceNSRVTFS
Bait Uniprot AccessionQ12972
Bait Uniprot IdentifierPP1R8_HUMAN
Bait Gene NamePPP1R8
Bait OrganismHomo sapiens (Human)
Sequence Position198-204
Critical ResiduesP4; P6
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis; Phosphatase assay
Interaction ID20693
Interacting DomainCalcineurin-like phosphoesterase domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12657641
CommentsThe RVXF motif of human Nuclear inhibitor of protein phosphatase 1 (NIPP1) that mediates binding to the catalytic subunit of protein phosphatase 1 (PP1c)


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)