Instance ID10696
Regular Expressionxx[RK]x{0,1}[VIL][^P][FW]x
Motif InstanceDRKKIQFS
Bait Uniprot AccessionQ9UD71
Bait Uniprot IdentifierPPR1B_HUMAN
Bait Gene NamePPP1R1B
Bait OrganismHomo sapiens (Human)
Sequence Position5-12
Critical ResiduesP2; P3; P5; P7
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis
Interaction ID20696
Interacting DomainCalcineurin-like phosphoesterase domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10075680, 9108011
CommentsThe RVXF motif of human DARPP-32 (PPP1R1B) that mediates binding to the catalytic subunit of protein phosphatase 1 (PPP1CA) at a site removed from the active site and that this interaction is not directly involved in inhibition of enzyme activity

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)