Instance ID10697
Regular Expressionxx[RK]x{0,1}[VIL][^P][FW]x
Motif InstanceKRKSVTWP
Bait Uniprot AccessionQ96QC0
Bait Uniprot IdentifierPP1RA_HUMAN
Bait Gene NamePPP1R10
Bait OrganismHomo sapiens (Human)
Sequence Position395-402
Critical ResiduesP5; P7
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis
Interaction ID20697
Interacting DomainCalcineurin-like phosphoesterase domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12574161
CommentsThe RVXF motif of human PNUTS, Phosphatase 1 NUclear Targeting Subunit (PPP1R10), that mediates high affinity binding to the catalytic subunit of protein phosphatase 1 (PPP1CA) and inhibition of PP1 activity

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)