Instance ID10709
Regular Expressionxx[RK]x{0,1}[VIL][^P][FW]x
Motif InstanceKKKVHFS
Bait Uniprot AccessionP51955
Bait Uniprot IdentifierNEK2_HUMAN
Bait Gene NameNEK2
Bait OrganismHomo sapiens (Human)
Sequence Position381-387
Critical ResiduesP6
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Co-IP; Y2H; Co-IP; Mutation analysis
Interaction ID20709
Interacting DomainCalcineurin-like phosphoesterase domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10880350
CommentsThe RVXF motif in the C-terminal region of the cell cycle-regulated protein serine/threonine NIMA-related kinase 2 (NEK2) that mediates binding to the catalytic subunit of protein phosphatase 1 (PPP1CA)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)