Instance ID10710
Regular ExpressionxP[^P]I[^P][IV][^P]
Motif InstanceIPQIVID
Bait Uniprot AccessionQ6VV64
Bait Uniprot IdentifierKCNKI_MOUSE
Bait Gene NameKcnk18
Bait OrganismMus musculus (Mouse)
Sequence Position209-215
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Pull down
Interaction ID20710
Interacting DomainCalcineurin-like phosphoesterase domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16569637
CommentsTargeting of the mouse Calmodulin-dependent calcineurin A subunit alpha isoform (Ppp3ca) to the Calcineurin (PP2B) docking motif in mouse Two-pore-domain potassium channel TRESK (Kcnk18) is required for the calcium-dependent activation of TRESK

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)