Instance ID10719
Regular ExpressionxP[TS]APx
Motif InstanceEPTAPP
Bait Uniprot AccessionP04591
Bait Uniprot IdentifierGAG_HV1H2
Bait Gene Namegag
Bait OrganismHuman immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1)
Sequence Position454-459
Critical ResiduesP2; P5; P6
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)NMR; Electron microscopy; Alanine scanning; SPR; Mutation analysis; Co-IP; Y2H; Competition binding
Interaction ID20719
Interacting DomainUEV domain
Disease Association(s)Human immunodeficiency virus (HIV) infection
Inhibitor(s)Unknown
Reference(s)12379843, 11595185, 11427703, 11805336
CommentsThe UEV Domain binding P[TS]AP motif in Gag polyprotein of Human immunodeficiency virus type 1 group M subtype B that mediates binding to the UEV domain of human Tumor susceptibility gene 101 protein (TSG101)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)