Instance ID10720
Regular ExpressionxP[TS]APx
Motif InstanceTPTAPQ
Bait Uniprot AccessionQ6UWE0
Bait Uniprot IdentifierLRSM1_HUMAN
Bait Gene NameLRSAM1
Bait OrganismHomo sapiens (Human)
Sequence Position648-653
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Y2H
Interaction ID20720
Interacting DomainUEV domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15256501
CommentsBivalent binding of the UEV domain of human Tumor susceptibility gene 101 protein (TSG101) to the PTAP motif (648-653) of human TAL (TSG101-associated ligase), also known as E3 ubiquitin-protein ligase LRSAM1, is essential for TAL-mediated ubiquitylation of TSG101

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)