Instance ID10728
Regular ExpressionxP[TS]APx
Motif InstancePPSAPS
Bait Uniprot AccessionO14828
Bait Uniprot IdentifierSCAM3_HUMAN
Bait Gene NameSCAMP3
Bait OrganismHomo sapiens (Human)
Sequence Position63-68
Critical ResiduesP5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)SPR; Mutation analysis
Interaction ID20728
Interacting DomainUEV domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19158374
CommentsHuman Secretory carrier-associated membrane protein SCAMP3 localizes in part to early endosomes and negatively regulates EGFR degradation through processes that involve its ubiquitylation and interactions with the UEV domain of human ESCRT-I complex subunit TSG101

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)