Instance ID10734
Regular ExpressionxP[TS]APx
Motif InstanceTPSAPV
Bait Uniprot AccessionO14964
Bait Uniprot IdentifierHGS_HUMAN
Bait Gene NameHGS
Bait OrganismHomo sapiens (Human)
Sequence Position347-352
Critical ResiduesP2; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography; Mutation analysis
Interaction ID20734
Interacting DomainUEV domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)21070952, 12802020
CommentsThe UEV Domain binding P[TS]AP motif in Human Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS) that mediates binding to the UEV domain of human ESCRT-I complex subunit TSG101

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)