Instance ID10739
Regular Expression(x[^P]xNPx[FY]x)|(x[ILVMFY]xNxx[FY]x)
Motif InstanceTGENPIYK
Bait Uniprot AccessionP05556
Bait Uniprot IdentifierITB1_HUMAN
Bait Gene NameITGB1
Bait OrganismHomo sapiens (Human)
Sequence Position777-784
Critical ResiduesP7
Motif PTM(s)Unknown
Secondary StructureBeta turn
Experimental Method(s)Mutation analysis
Interaction ID20739
Interacting DomainPTB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12606711
CommentsThe NPxY motif (777-784) in human Integrin beta-1 (ITGB1) that mediates its interaction with the phosphotyrosine-binding (PTB) domain of human Epidermal growth factor receptor kinase substrate 8 (EPS8)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)