Instance ID10746
Regular Expression(x[^P]xNPx[FY]x)|(x[ILVMFY]xNxx[FY]x)
Motif InstanceTVVNPKYE
Bait Uniprot AccessionP05556
Bait Uniprot IdentifierITB1_HUMAN
Bait Gene NameITGB1
Bait OrganismHomo sapiens (Human)
Sequence Position789-796
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureBeta turn
Experimental Method(s)Co-IP; Alanine scanning; Pull down; Y2H
Interaction ID20746
Interacting DomainPTB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11741908
CommentsInteraction between the phosphotyrosine-binding (PTB) domain of human ICAP1 alpha and the NPXY motif (789-796) of human Integrin beta-1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)