Instance ID10747
Regular Expression(x[^P]xNPx[FY]x)|(x[ILVMFY]xNxx[FY]x)
Motif InstanceNFDNPVYR
Bait Uniprot AccessionQ14114
Bait Uniprot IdentifierLRP8_HUMAN
Bait Gene NameLRP8
Bait OrganismHomo sapiens (Human)
Sequence Position860-867
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)ITC; Pull down; X-ray crystallography
Interaction ID20747
Interacting DomainPTB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12737822
CommentsInteraction between the phosphotyrosine binding (PTB) domain of the Mouse adaptor protein Disabled-1 (Dab1) and the NPXY motif of human Reelin, the very low-density lipoprotein receptor, the Apolipoprotein E receptor 2 (APOER2/LRP8)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)