Instance ID10753
Regular Expression(x[^P]xNPx[FY]x)|(x[ILVMFY]xNxx[FY]x)
Motif InstanceVFTNAAFD
Bait Uniprot AccessionP16109
Bait Uniprot IdentifierLYAM3_HUMAN
Bait Gene NameSELP
Bait OrganismHomo sapiens (Human)
Sequence Position820-827
Critical ResiduesP2; P7
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Site-directed mutagenesis; Y2H; SPR
Interaction ID20753
Interacting DomainPTB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19138666
CommentsThe N-terminal phosphotyrosine-binding (PTB) domain of Human Numb3 (NUMB) binds to the cytosolic tail of the leukocyte adhesion receptor P-selectin (SELP)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)