Instance ID10755
Regular Expression(x[^P]xNPx[FY]x)|(x[ILVMFY]xNxx[FY]x)
Motif InstanceGFSNMSFE
Bait Uniprot AccessionQ9U485
Bait Uniprot IdentifierQ9U485_DROME
Bait Gene NameNak
Bait OrganismDrosophila melanogaster (Fruit fly)
Sequence Position1439-1446
Critical ResiduesP2; P4; P7
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)NMR; Alanine scanning
Interaction ID20755
Interacting DomainPTB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10747019
CommentsHigh-affinity binding of the Drosophila Numb phosphotyrosine-binding (PTB) domain to the NPXY motif of Drosophila Numb-associated kinase (Nak)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)