Instance ID10756
Regular Expression(x[^P]xNPx[FY]x)|(x[ILVMFY]xNxx[FY]x)
Motif InstanceSVPNPVFG
Bait Uniprot AccessionQ9NY15
Bait Uniprot IdentifierSTAB1_HUMAN
Bait Gene NameSTAB1
Bait OrganismHomo sapiens (Human)
Sequence Position2536-2543
Critical ResiduesP4; P7
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Competition binding; Pull down; Alanine scanning
Interaction ID20756
Interacting DomainPTB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20599701
CommentsThe PTB domain of human adapter protein GULP is able to specifically interact with the NPxF/Y motif of human phagocytic receptor Stabilin-1 (STAB1) cytoplasmic region thus functioning as an adaptor protein for Stabilin-1-mediated phagocytosis

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)