Instance ID10774
Regular ExpressionF[EDQS][MILV][ED][MILV]((x{0,1}[ED])|($))
Motif InstanceFEMDI
Bait Uniprot AccessionQ13541
Bait Uniprot Identifier4EBP1_HUMAN
Bait Gene NameEIF4EBP1
Bait OrganismHomo sapiens (Human)
Sequence Position114-118
Critical ResiduesP1; P2; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Western blot; Pull down; Mutation analysis
Interaction ID20774
Interacting DomainWD40 repeat domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12912989
CommentsThe TOS motif in human translational repressor protein EIF4EBP1 (4E-BP1, also termed PHAS-I) acts as a docking site for the human TOR pathway adaptor protein RAPTOR

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)