Instance ID10776
Regular Expression[LI]xCx[DE]
Motif InstanceLYCAE
Bait Uniprot AccessionP35869
Bait Uniprot IdentifierAHR_HUMAN
Bait Gene NameAHR
Bait OrganismHomo sapiens (Human)
Sequence Position331-335
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H
Interaction ID20776
Interacting DomainB domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)10644764
CommentsThe LxCxE motif in the Human dioxin aromatic hydrocarbon receptor (AHR) that mediates binding to a highly conserved shallow groove in the B domain of the human retinoblastoma protein (RB)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)