Instance ID10782
Regular Expression[LI]xCx[DE]
Motif InstanceLKCFE
Bait Uniprot AccessionQ99683
Bait Uniprot IdentifierM3K5_HUMAN
Bait Gene NameMAP3K5
Bait OrganismHomo sapiens (Human)
Sequence Position916-920
Critical ResiduesP1; P2; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down(GST tag)
Interaction ID20782
Interacting DomainB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15210709
CommentsThe Rb-binding LxCxE motif in the Human apoptosis signal-regulating kinase ASK1 (MAP3K5) that mediates binding to the human retinoblastoma protein (RB)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)