Instance ID10786
Regular Expression[LI]xCx[DE]
Motif InstanceLVCQE
Bait Uniprot AccessionP35251
Bait Uniprot IdentifierRFC1_HUMAN
Bait Gene NameRFC1
Bait OrganismHomo sapiens (Human)
Sequence Position663-667
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis
Interaction ID20786
Interacting DomainB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11336696
CommentsThe Rb-binding LxCxE motif in the Human Replication factor C large subunit (RFC1) that mediates binding to the human retinoblastoma protein (RB) and thereby promotes cell survival after DNA damage

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)