Instance ID10790
Regular Expression[LI]xCx[DE]
Motif InstanceLTCEE
Bait Uniprot AccessionP51531
Bait Uniprot IdentifierSMCA2_HUMAN
Bait Gene NameSMARCA2
Bait OrganismHomo sapiens (Human)
Sequence Position1294-1298
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP
Interaction ID20790
Interacting DomainB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9326598
CommentsThe Rb-binding LxCxE motif in the Human ATP-dependent helicase SMARCA2 that mediates binding to the human retinoblastoma protein (RB) to repress S-phase-inducing transcription factor E2F1, thereby preventing cells from entering S phase

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)