Instance ID10796
Regular Expression[LI]xCx[DE]
Motif InstanceLACSD
Bait Uniprot AccessionP06726
Bait Uniprot IdentifierPP71_HCMVA
Bait Gene NameUL82
Bait OrganismHuman cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
Sequence Position216-220
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Western blot; Pull down; Mutation analysis
Interaction ID20796
Interacting DomainB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12612064
CommentsThe Rb-binding LxCxE motif in the Human cytomegalovirus pp71 (UL82) that mediates binding to the human retinoblastoma protein (RB) and induces DNA synthesis in quiescent cells

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)