Instance ID10804
Regular Expression[LI]xCx[DE]
Motif InstanceLRCHE
Bait Uniprot AccessionO75150
Bait Uniprot IdentifierBRE1B_HUMAN
Bait Gene NameRNF40
Bait OrganismHomo sapiens (Human)
Sequence Position109-113
Critical ResiduesP1; P3; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Mutation analysis
Interaction ID20804
Interacting DomainB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10944455
CommentsThe Rb-binding LxCxE motif in the Human E3 ubiquitin-protein ligase BRE1B/RBP95/RNF40, a novel leucine zipper protein, that mediates binding to the human retinoblastoma protein (RB)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)