Instance ID10806
Regular Expression[LI]xCx[DE]
Motif InstanceLFCSE
Bait Uniprot AccessionP03070
Bait Uniprot IdentifierLT_SV40
Bait Gene NameNot Available
Bait OrganismSimian virus 40 (SV40)
Sequence Position103-107
Critical ResiduesP1; P3; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Mutation analysis; X-ray crystallography
Interaction ID20806
Interacting DomainB domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)2839300, 11226179
CommentsThe Rb-binding LxCxE motif in the SV40 large T antigen that mediates binding to the human retinoblastoma protein (RB)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)