Instance ID10826
Regular Expression[LIVMP]x{0,2}(T)PxxE
Motif InstancePPTPPPE
Bait Uniprot AccessionP03070
Bait Uniprot IdentifierLT_SV40
Bait Gene NameNot Available
Bait OrganismSimian virus 40 (SV40)
Sequence Position699-705
Critical ResiduesP3
Motif PTM(s)Phosphorylation at Thr-P3
Secondary StructureUnknown
Experimental Method(s)Co-IP; Classical fluorescence spectroscopy; Mutation analysis
Interaction ID20826
Interacting DomainWD40 repeat domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)15611062
CommentsThe SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with the F box protein FBW7/FBXW7/hCdc4

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)